Sleep to Upscale, Sleep to Downscale: Balancing Homeostasis and Plasticity
نویسندگان
چکیده
The synaptic homeostasis hypothesis of sleep proposes that slow wave sleep (SWS) causes downscaling of synaptic networks potentiated during information uptake in prior wakefulness. Two studies in Neuron challenge this mechanism. Chauvette et al. (2012) show that SWS mediates an up- rather than downregulation of excitatory postsynaptic potential responses. Grosmark et al. (2012) find that downscaling in hippocampal networks might be mediated through REM sleep theta rather than SWS.
منابع مشابه
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ورودعنوان ژورنال:
- Neuron
دوره 75 شماره
صفحات -
تاریخ انتشار 2012